The TRIM2 Rabbit Polyclonal Antibody from Bioassay Technology Laboratory is a Rabbit Polyclonal antibody. This antibody recognizes Human, Mouse, and Rat antigen. The TRIM2 Rabbit Polyclonal Antibody has been validated for the following applications: Western Blot.
Description
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains: a RING: a B-box type 1 and a B-box type 2: and a coiled-coil region. The protein localizes to cytoplasmic filaments. It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins. Mutations in this gene can cause early-onset axonal neuropathy. Alternative splicing results in multiple transcript variants